I would shoot 4k. Hopefully, once you're framed and shooting, the camera will be settled on something, preferably some sort of tripod, and still.
"Somewhere in the middle" of the range usually works best for aperture. Don't go too very small or you'll get diffraction and the image will go soft. Better get the lights closer than go very wide, unless you specifically want a shallow depth of field.
Longer light arms give more options including backlighting. But if it's your first time then try one from the front and one from the side, or just a single light from one side or directly above before getting too fancy with backlighting.
For me, the Keldan 4x are too wide for macro. More backscatter gets lit up and it's difficult not to light the background as well as the subject. I 3D printed shades for mine but then eventually changed to narrower FIX lights.
Framing.... Try to get at least one wide establishing shot. Often you can do this after getting your tight shots as it's usually easier and faster to get. Also try to get low down so you can see more distant background to give shots depth.